This video is going to thread together three seemingly unrelated topics — (1) the Sugar Diet, (2) protein restriction, and (3) longevity— to reveal a fascinating metabolic link. We’ll work through each in turn. Drawing on data from Nature Metabolism, Cell Metabolism, and an N = 1+ experiment, we will explore how FGF-21, a key metabolic hormone, sits at center stage of this complex metabolic story. Could FGF-21 be the metabolic holy grail of longevity? Even if not, what can these data reveal to us? We’ll dive into the latest research and discuss how this hormone connects sugar, protein restriction, and long life. If you’re open to the data, you may find this biological puzzle both humbling and mystifying.
PRODUCTS
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STAYCURIOUS METABOLISM NEWSLETTER
For all references, a written breakdown, and even more information, see the associated StayCurious Metabolism Newsletter: https://staycuriousmetabolism.substack.com/p/the-sugar-diet-protein-restriction?r=40ekz2
For more written breakdowns, make sure to check out the StayCurious Metabolism Newsletter at https://StayCuriousMetabolism.com
PAST VIDEOS
Conversation with Physionic on the Sugar Diet: COMING SOON (Calendar swap)
Prior video on the Sugar Diet: https://youtu.be/IAc_7r_hVI8
CHAPTERS
0:00 – Sugar Diet, Protein Restriction, and Longevity
0:37 – Sugar Diet: Is It a Legit Health Strategy or Sugar Psychosis?
1:42 – How Protein Restriction Boosts FGF-21 to Enhance Metabolism
3:07 – Testing Protein Restriction on a 4:1 Ketogenic Diet
7:02 – FGF-21 and Longevity: The Metabolic Holy Grail?
9:14 – What Does This All Mean for Longevity and Metabolic Health?
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